Table 1
Peaks of Activation of Valance significantly modulated by valence within our regions of interest (orbitofrontal cortex, subgenual and anterior cingulate, insula, amygdala, brain stem, pons, and striatum as defined by the Wake Forest University Pickatlas), reported in standardized Montreal Neurological Institute coordinates
| Cluster size | Peak T | SVC P | Peak Z | x, y, z (mm) | Anatomical region |
|---|---|---|---|---|---|
| Valence (increasing)—positive words | |||||
| 21 | 3.9 | 0.03 | 3.7 | 42, 42, −10 | Lateral orbitofrontal cortex** |
| 13 | 3.8 | 0.04 | 3.6 | 30, 20, −8 | Anterior insula** |
| 9 | 3.4 | 0.05 | 3.3 | 32, 46, −14 | Lateral orbitofrontal cortex** |
| Valence (increasing)—negative words | |||||
| 24 | 3.7 | 0.04 | 3.6 | 34, 22, −24 | Posterior insula** |
| 20 | 3.6 | 0.01 | 3.5 | −2, 46, 10 | Anterior cingulate** |
| 7 | 3.5 | 0.06 | 3.4 | −2, 26, −10 | Subgenual cingulate |
| 3 | 3.3 | 0.05 | 3.2 | 50, 28, −12 | Lateral orbitofrontal cortex** |
| 13 | 3.6 | 0.07 | 3.5 | −14, −16, −22 | Brain stem |
| 18 | 3.6 | 0.03 | 3.5 | 0, 26, −10 | Subgenual cingulate** |
| 5 | 3.3 | 0.06 | 3.2 | 12, 38, −12 | Subgenual cingulate |
| Valence (increasing U-shaped model) | |||||
| 67 | 2.6 | 0.01 | 4 | 36, 20, −18 | Lateral orbitofrontal cortex** |
| 33 | 2.4 | 0.03 | 3.7 | −2, 42, 12 | Anterior cingulate** |
| 32 | 2.3 | 0.05 | 3.6 | 0, 26, −4 | Subgenual cingulate** |
| 18 | 2.3 | 0.09 | 3.6 | −54, 26, −4 | Operculum |
| 2 | 2.1 | 0.01 | 3.3 | 50, 42, −14 | Lateral orbitofrontal cortex** |
Note: Only regions showing a strong trend (P ≤ 0.1 SVC) are reported
**those significant at P = 0.05 are marked with a dual asterisk.
SVC, small volume correction.
